What is epigenetic and how it relates to obesity?

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Nongenetic factors that promote weight gain

Today, obesity is a multifactorial disease in which not only the genetic influences. Moreover, there are other non-genetic factors that favor weight gain. Therefore, I find it interesting to know some new terms such as what is an epigenetic process and how it relates to obesity.

Because not only the genetics and heredity influences obesity or overweight, science has investigated the implications of different epigenetic processes. But to begin to understand a little more these new terms, you need to know its definition.

What is epigenetics?

Epigenetics is the study of all non-genetic factors involved in the development of a disease or condition, in this case obesity. Epigenetic is the set of chemical processes that modify the activity of DNA without altering its sequence. The magnitude of changes varies with each person’s predisposition. Those with more predisposition to overweight, have a higher chance of epigenetic changes.

Now that you know what it is, it is interesting to relate the process of weight gain.

How is it related to being overweight?

19743987-modelo-nucleosome-molecular-el-nucleosoma-se-compone-de-una-doble-h-lice-de-adn-envuelto-alrededor-dThere are scientific studies that support that obese and people with other metabolic problems such as diabetes, have different epigenetic marks to thin and non-diabetics.

These epigenetic changes are due to bad and incorrect environmental and dietary habits, as well as the lack of healthy habits related to physical activity.

A sedentary lifestyle and high calorie Western diet, high in fat and rich in simple sugars, added stress and other factors are responsible for the production of genetic changes that lead, in turn, the emergence of other diseases associated with being overweight, as for example the metabolic syndrome.

In this syndrome they are altered several parameters such as glucose, cholesterol, triglycerides, etc. The way to reverse this situation and stop epigenetic changes is hindering factors I mentioned earlier.

These changes depend on you. You can be genetically thin, but if you eat improperly and are sedentary, have high chances to change your DNA, which can predispose to future generations to overweight.

On the other hand, we must not forget that, who have a greater chance of suffering from obesity, is not conditioned for life to be, as you may care to diet and exercise and can reverse this situation.

In short, being obese or not, largely it depends on you. To change this situation, you need decision, perseverance and love yourself.

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